Publications

2026 Journal Article

Alappat M, Mazurkiewicz M, Zambounis I, Mastrangelo A, Algaba Martinez VM, Grampp T, Prisco F, Kipar A, Picard A, Bhat MA, Benke D, Zeilhofer HU, Thorens B, Gaspari S. (2026)Tmem117, an oligodendrocyte-enriched regulator of NCX activity, links myelin homeostasis to counterregulation and metabolic health Responses to Chronic Stress and Ketamine PNAS

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2024 (no affiliation to University of Zurich)

Mitsi V, Ruiz A, Polizu C, Farzinpour Z, Ramakrishnan A, Serafini RA, Parise EM, Floodstrand M, Sial OK, Gaspari S, Tang CY, Nestler EJ, Schmidt EF, Shen L, ZHachariou V. (2024)RGS4 Actions in Mouse Prefrontal Cortex Modulate Behavioral and Transcriptomic Responses to Chronic Stress and Ketamine Molecular Pharmacology

2023

Pryce KD, Serafini RA, Ramakrishnan A, Nicolais A, Giosan IM, Polizu C, Torres-Berrío A, Vuppala S, Kronman H, Ruiz A, Gaspari S, Peña CJ, Sakloth F, Mitsi V, van Duzer J, Mazitschek R, Jarpe M, Shen L, Nestler EJ, Zachariou V. (2023) Oxycodone withdrawal induces HDAC1/HDAC2-dependent transcriptional maladaptations in the reward pathway in a mouse model of peripheral nerve injuryNat Neurosci.

Katsioudi G, Dreos R, Arpa ES, Gaspari S, Liechti A, Sato M, Gabriel CH, Kramer A, Brown SA, Gatfield D. (2023)A conditional Smg6 mutant mouse model reveals circadian clock regulation through the nonsense-mediated mRNA decay pathway Sci. Adv.

Gaspari S, Labouèbe G, Picard A, Berney X, Rodriguez Sanchez-Archidona A, Thorens B. (2023) Tmem117 in AVP neurons regulates the counterregulatory response to hypoglycemia. bioRxiv

2022

Gaspari S, Quenneville S, Rodriguez-Sanchez-Archidona A, Thorens B, Croizier S. (2022) Structural and molecular characterization of paraventricular thalamic glucokinase-expressing neuronal circuits in the mouse. J. Comp. Neurol.

2021

Kessler S*, Labouèbe G*, Croizier S*, Gaspari S, Tarussio D, Thorens B. (2021) Glucokinase neurons of the paraventricular nucleus of the thalamus sense glucose and decrease food consumption. iScience

2019

Avrampou K, Pryce KD, Ramakrishnan A, Sakloth F, Gaspari S, Serafini RA, Mitsi V, Polizu C, Swartz C, Ligas B, Richards A, Shen L, Carr FB, Zachariou V. (2019) RGS4 maintains chronic pain symptoms in rodent models.  J Neurosci.

2018

Gaspari S, Purushothaman I, Cogliani V, Sakloth F, Neve RL, Howland D, Ring RH, Ross EM, Shen L, Zachariou V. (2018) Suppression of RGSz1 function optimizes the actions of opioid analgesics by mechanisms that involve the Wnt/β-catenin pathway. PNAS

2017

Gaspari S, Cogliani V, Manouras L, Anderson EM, Mitsi V, Avrampou K, Carr FB, Zachariou V. (2017) RGS9-2 modulates responses to oxycodone in pain-free and chronic pain states. Neuropsychopharmacology

Descalzi G, Mitsi V, Purushothaman I, Gaspari S, Avrampou K, Loh YH, Shen L, Zachariou V. (2017) Neuropathic pain promotes adaptive changes in gene expression in brain networks involved in stress and depression. Sci. Signal.

2016

Gacias M, Gaspari S, Santos PM, Tamburini S, Andrade M, Zhang F, Shen N, Tolstikov V, Kiebish MA, Dupree JL, Zachariou V, Clemente JC, Casaccia P. (2016) Microbiota-driven transcriptional changes in prefrontal cortex override genetic differences in social behavior. elife

2015

Mitsi V, Terzi D, Purushothaman I, Manouras L, Gaspari S, Neve RL, Stratinaki M, Feng J, Shen L, Zachariou V. (2015) RGS9-2–controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states. PNAS

2014

Terzi D, Gaspari S, Manouras L, Descalzi G, Mitsi V, Zachariou V. (2014) RGS9-2 modulates sensory and mood related symptoms of neuropathic pain.  Neurobiol Learn Mem.

Gaspari S*, Papachatzaki MM*, Koo JW, Carr FB, Tsimpanouli ME, Stergiou E, Bagot RC, Ferguson D, Mouzon E, Chakravarty S, Deisseroth K, Lobo MK, Zachariou V. (2014) Nucleus accumbens-specific interventions in RGS9-2 activity modulate responses to morphine. Neuropsychopharmacology