PUBLICATIONS
ZORA Publication List
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Publications
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2021
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Journal Article
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Adeno-Associated Virus-Mediated Gain-of-Function mPCSK9 Expression in the Mouse Induces Hypercholesterolemia, Monocytosis, Neutrophilia, and a Hypercoagulative State. Frontiers in Cardiovascular Medicine, 8:718741.
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2020
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Journal Article
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Bidirectional regulation of distinct memory domains by α5-subunit-containing GABA$_{A}$ receptors in CA1 pyramidal neurons. Learning & memory (Cold Spring Harbor, N.Y.), 27(10):423-428.
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Astrocyte dysfunction increases cortical dendritic excitability and promotes cranial pain in familial migraine. Science Advances, 6(23):aaz1584.
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2019
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Journal Article
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Differences in glutamate uptake between cortical regions impact neuronal NMDA receptor activation. Communications Biology, 2:127.
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2018
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Journal Article
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Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors. Nature Communications, 9(1):3230.
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Impact on GABA systems in monogenetic developmental CNS disorders: clues to symptomatic treatment. Neuropharmacology, 136:46-55.
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Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia. Molecular Psychiatry, 23(2):323-334.
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2017
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Journal Article
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2016
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Journal Article
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The positive allosteric GABAB receptor modulator rac-BHFF enhances baclofen-mediated analgesia in neuropathic mice.. Neuropharmacology, 108:172-178.
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K63-Linked Ubiquitination of GABAB1 at Multiple Sites by the E3 Ligase Mind Bomb-2 Targets GABAB Receptors to Lysosomal Degradation. Journal of Biological Chemistry, 291(41):21682-21693.
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Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain. Journal of Clinical Investigation, 126(7):2547-2560.
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A pharmacogenetic 'restriction-of-function' approach reveals evidence for anxiolytic-like actions mediated by α5-containing GABAA receptors in mice. Neuropsychopharmacology, 41(10):2492-2501.
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Book Section
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Molecular organization, trafficking, and degradation of the GABA-B receptor. In: Colombo, Giancarlo. GABA-B Receptor. Cham: Humana Press, 55-74.
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2015
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Journal Article
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Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference. Journal of Neuroscience, 35(40):13698-13712.
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Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype. Nature Communications, 6(6803):online.
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Book Section
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Regulation of cell surface GABA(B) receptors: contribution to synaptic plasticity in neurological diseases. In: Rudolph, Uwe. Diversity and functions of GABA receptors: a tribute to Hanns Möhler, Part B. Burlington: Elsevier, 41-70.
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2014
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Journal Article
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Ischemia-like oxygen and glucose deprivation mediates down-regulation of cell surface γ-aminobutyric acidB receptors via the endoplasmic reticulum (ER) stress-induced transcription factor CCAAT/enhancer-binding protein (C/EBP)-homologous protein (CHOP). Journal of Biological Chemistry, 289(18):12896-12907.
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Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites. Neuropsychopharmacology, 39(2):477-487.
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Pagination
2014 |
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Zemoura K. and Benke D. (2014) Proteasomal degradation of γ-aminobutyric acidB receptors is mediated by the interaction of the GABAB2 C terminus with the proteasomal ATPase Rtp6 and regulated by neuronal activity. J. Biol. Chem. 289, 7738-7746. |
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2010 | |
Mohler H., Benke, D., Rudolph, U. and Fritschy, J.-M. (2010) GABAA receptors. |
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2007 | |
Grampp, T., Sauter, K., Markovic, B. and Benke, D. (2007). γ-Aminobutyric acid type B receptors are constitutively internalized via the clathrin-dependent pathway and targeted to lysosomes for degradation. |
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2006 | |
Studer, R., von Boehmer, L., Haenggi, T., Schweizer, C., Benke, D., Rudolph, U. and Fritschy J.-M. (2006). Alteration of GABAergic synapses and gephyrin clusters in the thalamic reticular nucleus of GABAA receptor α3 subunit-null mice. Eur. J. Neurosci. 24, 1307-1315 |
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Yee, B. K., Balic, E., Singer, P., Schwerdel, C., Grampp, T., Gabernet, L., Knuesel, I., Benke, D., Feldon, J., Mohler, H. and Boison, D. (2006).Disruption of glycine transporter 1 restricted to forebrain neurons is associated with a pro-cognitive and anti-psychotic phenotypic profile. J. Neurosci. 26, 3169-3181 |
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2005 | |
Yee, B.K., Keist, R., von Boehmer, L., Studer, R., Benke, D., Hagenbuch, N., Dong, Y., Malenka, R.C., Fritschy, J.-M., Bluethmann, H., Feldon, J., Möhler, H., Rudolph, U. (2005). A schizophrenia-related sensorimotor deficit links α3-containing GABAA receptors to a dopamine hyperfunction. Proc. Natl. Acad. Sci. USA 102, 17154-17159. |
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Sauter, K., Grampp, T., Fritschy, J.-M., Kaupmann, K., Bettler, B., Mohler, H. and Benke, D. (2005). Subtype-selective interaction with the transcription factor CAAT/enhancer-binding protein (C/EBP) homologous protein (CHOP) regulates cell surface expression of GABAB receptors. J. Biol. Chem. 280, 33566-33572 |
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2004 | |
Benke, D., Fakitsas, P., Rogenmoser, C., Michel, C., Rudolph, U. and Mohler, H. (2004). Analysis of the presence and abundance of GABAA receptors containing two different types of α subunits in murine brain using point-mutated α-subunits. J. Biol. Chem. 279, 43654-43660 |
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Fritschy, J.-M., Sidler, C., Parpan, F., Gassmann, M., Kaupmann, K., Bettler, B., and Benke, D. (2004). Independent maturation of the GABAB receptor subunits GABAB1 and GABAB2 during postnatal development in rodent brain. J. Comp. Neurol. 477, 235-252 | |
2002 | |
Benke, D. Michel, C. and Mohler, H. (2002). Structure of GABAB receptors in rat retina. J. Recep. Sign. Transduc. Res. 22, 253-266 Structure of GABAB receptors in rat retina. J. Recep. Sign. Transduc. Res. 22, 253-266 |
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Crestani, F., Keist, R., Fritschy, J.-M., Benke, D., Vogt, K., Prut, L., Blüthmann, H., Mohler, H. and Rudolph, U. (2002). Trace fear conditioning involves hippocampal α5 GABAA receptors. Proc. Natl. Acad. Sci. USA 99, 8980-8985 |
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Gao, B., Wenzel, A., Grimm, C., Vavricka, S. R., Benke, D., Meier, P. J., Remè, C. E. (2002). Localization of organic anion transport protein 2 in the apical region of rat retina pigment epithelium. Invest. Ophtha. Visual Sci. 43, 510-514 Localization of organic anion transport protein 2 in the apical region of rat retina pigment epithelium. Invest. Ophtha. Visual Sci. 43, 510-514 |
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2001 | |
Benke, D., Olah, A. and Mohler, H. (2001). Bio-Oss bone substitute contains carbonate but fails to display protein including TGFβ. Biomaterials 22, 1005-1012 |
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2000 | |
Löw., K., Crestani, F., Keist, R., Benke, D., Brünig, I., Benson, J. A., Fritschy, J.-M., Rülicke, T., Bluethmann, H., Mohler, H. and Rudolph, U. (2000). Molecular and neuronal substrate for the selective attenuation of anxiety. Science 290, 131-134 Science 290, 131-134 |
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Gao, B., Hagenbuch, B., Kullak-Ublick, G. A., Benke, D., Aguzzi, A. and Meier, P. J. (2000). Organic anion-transporting polypeptides mediate transport of opioid peptides across the blood-brain barrier. J. Pharmacol. Exp. Therap. 294, 73-79 Organic anion-transporting polypeptides mediate transport of opioid peptides across the blood-brain barrier. J. Pharmacol. Exp. Therap. 294, 73-79 |
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Lorez, M., Benke, D., Lüscher, B., Mohler, H. and Benson, J. A. (2000). Single-channel properties of neuronal GABAA receptors from mice lacking the γ2-subunit. J. Physiol. 527.1, 11-31 |
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Sibille, E., Pavlides, C., Benke, D. and Toth, M. (2000). Genetic inactivation of the serotonin1A receptor in mice results in downregulation of major GABAA receptor alpha subunits, reduction of GABAA receptor binding, and benzodiazepine-resistant anxiety. J. Neurosci. 20, 2758-2765. |
Publications before year 2000
ZORA Publication List
Download Options
Publications
-
2020
-
Journal Article
-
Bidirectional regulation of distinct memory domains by α5-subunit-containing GABA$_{A}$ receptors in CA1 pyramidal neurons. Learning & memory (Cold Spring Harbor, N.Y.), 27(10):423-428.
-
Astrocyte dysfunction increases cortical dendritic excitability and promotes cranial pain in familial migraine. Science Advances, 6(23):aaz1584.
-
-
-
2019
-
Journal Article
-
Differences in glutamate uptake between cortical regions impact neuronal NMDA receptor activation. Communications Biology, 2:127.
-
-
2018
-
Journal Article
-
Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors. Nature Communications, 9(1):3230.
-
Impact on GABA systems in monogenetic developmental CNS disorders: clues to symptomatic treatment. Neuropharmacology, 136:46-55.
-
Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia. Molecular Psychiatry, 23(2):323-334.
-
-
-
2017
-
Journal Article
-
-
2016
-
Journal Article
-
The positive allosteric GABAB receptor modulator rac-BHFF enhances baclofen-mediated analgesia in neuropathic mice.. Neuropharmacology, 108:172-178.
-
K63-Linked Ubiquitination of GABAB1 at Multiple Sites by the E3 Ligase Mind Bomb-2 Targets GABAB Receptors to Lysosomal Degradation. Journal of Biological Chemistry, 291(41):21682-21693.
-
Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain. Journal of Clinical Investigation, 126(7):2547-2560.
-
A pharmacogenetic 'restriction-of-function' approach reveals evidence for anxiolytic-like actions mediated by α5-containing GABAA receptors in mice. Neuropsychopharmacology, 41(10):2492-2501.
-
-
Book Section
-
Molecular organization, trafficking, and degradation of the GABA-B receptor. In: Colombo, Giancarlo. GABA-B Receptor. Cham: Humana Press, 55-74.
-
-
-
2015
-
Journal Article
-
Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference. Journal of Neuroscience, 35(40):13698-13712.
-
Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype. Nature Communications, 6(6803):online.
-
-
Book Section
-
Regulation of cell surface GABA(B) receptors: contribution to synaptic plasticity in neurological diseases. In: Rudolph, Uwe. Diversity and functions of GABA receptors: a tribute to Hanns Möhler, Part B. Burlington: Elsevier, 41-70.
-
-
-
2014
-
Journal Article
-
Ischemia-like oxygen and glucose deprivation mediates down-regulation of cell surface γ-aminobutyric acidB receptors via the endoplasmic reticulum (ER) stress-induced transcription factor CCAAT/enhancer-binding protein (C/EBP)-homologous protein (CHOP). Journal of Biological Chemistry, 289(18):12896-12907.
-
Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites. Neuropsychopharmacology, 39(2):477-487.
-
-
-
2013
-
Journal Article
-
GABAB receptor trafficking and interacting proteins: Targets for the development of highly specific therapeutic strategies to treat neurological disorders?. Biochemical Pharmacology, 86(11):1525-1530.
-
-
Pagination
ZORA Publication List
Download Options
Publications
-
2020
-
Journal Article
-
Bidirectional regulation of distinct memory domains by α5-subunit-containing GABA$_{A}$ receptors in CA1 pyramidal neurons. Learning & memory (Cold Spring Harbor, N.Y.), 27(10):423-428.
-
Astrocyte dysfunction increases cortical dendritic excitability and promotes cranial pain in familial migraine. Science Advances, 6(23):aaz1584.
-
-
-
2019
-
Journal Article
-
Differences in glutamate uptake between cortical regions impact neuronal NMDA receptor activation. Communications Biology, 2:127.
-
-
2018
-
Journal Article
-
Itch suppression in mice and dogs by modulation of spinal α2 and α3GABAA receptors. Nature Communications, 9(1):3230.
-
Impact on GABA systems in monogenetic developmental CNS disorders: clues to symptomatic treatment. Neuropharmacology, 136:46-55.
-
Translational evaluation of translocator protein as a marker of neuroinflammation in schizophrenia. Molecular Psychiatry, 23(2):323-334.
-
-
-
2017
-
Journal Article
-
-
2016
-
Journal Article
-
The positive allosteric GABAB receptor modulator rac-BHFF enhances baclofen-mediated analgesia in neuropathic mice.. Neuropharmacology, 108:172-178.
-
K63-Linked Ubiquitination of GABAB1 at Multiple Sites by the E3 Ligase Mind Bomb-2 Targets GABAB Receptors to Lysosomal Degradation. Journal of Biological Chemistry, 291(41):21682-21693.
-
Phosphorylation state-dependent modulation of spinal glycine receptors alleviates inflammatory pain. Journal of Clinical Investigation, 126(7):2547-2560.
-
A pharmacogenetic 'restriction-of-function' approach reveals evidence for anxiolytic-like actions mediated by α5-containing GABAA receptors in mice. Neuropsychopharmacology, 41(10):2492-2501.
-
-
Book Section
-
Molecular organization, trafficking, and degradation of the GABA-B receptor. In: Colombo, Giancarlo. GABA-B Receptor. Cham: Humana Press, 55-74.
-
-
-
2015
-
Journal Article
-
Tonic Inhibitory Control of Dentate Gyrus Granule Cells by α5-Containing GABAA Receptors Reduces Memory Interference. Journal of Neuroscience, 35(40):13698-13712.
-
Analgesia and unwanted benzodiazepine effects in point-mutated mice expressing only one benzodiazepine-sensitive GABAA receptor subtype. Nature Communications, 6(6803):online.
-
-
Book Section
-
Regulation of cell surface GABA(B) receptors: contribution to synaptic plasticity in neurological diseases. In: Rudolph, Uwe. Diversity and functions of GABA receptors: a tribute to Hanns Möhler, Part B. Burlington: Elsevier, 41-70.
-
-
-
2014
-
Journal Article
-
Ischemia-like oxygen and glucose deprivation mediates down-regulation of cell surface γ-aminobutyric acidB receptors via the endoplasmic reticulum (ER) stress-induced transcription factor CCAAT/enhancer-binding protein (C/EBP)-homologous protein (CHOP). Journal of Biological Chemistry, 289(18):12896-12907.
-
Antihyperalgesia by α2-GABAA receptors occurs via a genuine spinal action and does not involve supraspinal sites. Neuropsychopharmacology, 39(2):477-487.
-
-
-
2013
-
Journal Article
-
GABAB receptor trafficking and interacting proteins: Targets for the development of highly specific therapeutic strategies to treat neurological disorders?. Biochemical Pharmacology, 86(11):1525-1530.
-
-