Looser ZJ, Faik Z, Ravotto L, Zanker HS, Jung RB, Werner HB, Ruhwedel T, Möbius W, Bergles DE, Barros LP, Nave KA, Weber B and Saab AS. Oligodendrocyte–axon metabolic coupling is mediated by extracellular K+ and maintains axonal health. Nature Neuroscience. 2024. doi: 10.1038/s41593-023-01558-3
Todorova V, Stauffacher MF, Ravotto L, Nötzli S, Karademir D, Ebner LJA, Imsand C, Merolla L, Hauck SM, Samardzija M, Saab AS, Barros LF, Weber B, Grimm C. Deficits in mitochondrial TCA cycle and OXPHOS precede rod photoreceptor degeneration during chronic HIF activation. Molecular Neurodegeneration. 2023. doi: 10.1186/s13024-023-00602-x
Hösli L, Zuend M, Bredell G, Zanker HS, Porto de Oliveira CE, Saab AS, Weber B. Direct vascular contact is a hallmark of cerebral astrocytes. Cell Reports. 2022. doi: 10.1016/j.celrep.2022.110599
Hösli L, Binini N, Ferrari KD, Thieren L, Looser ZJ, Zuend M, Zanker HS, Berry S, Holub M, Möbius W, Ruhwedel T, Nave KA, Giaume C, Weber B, Saab AS. Decoupling astrocytes in adult mice impairs synaptic plasticity and spatial learning. Cell Reports. 2022. doi: 10.1016/j.celrep.2022.110484
Glück C, Ferrari KD, Binini N, Keller A, Saab AS, Stobart JL, Weber B. Distinct signatures of calcium activity in brain mural cells. eLife. 2021. doi: 10.7554/eLife.70591
Passini FS, Jaeger PK, Saab AS, Hanlon S, Chittim NA, Arlt MJ, Ferrari KD, Haenni D, Caprara S, Bollhalder M, Niederöst B, Horvath AN, Götschi T, Ma S, Passini-Tall B, Fucentese SF, Blache U, Silván U, Weber B, Silbernagel KG, Snedeker JG. Shear-stress sensing by PIEZO1 regulates tendon stiffness in rodents and influences jumping performance in humans. Nature Biomedical Engineering. 2021. doi: 10.1038/s41551-021-00716-x
Zuend M, Saab AS, Wyss MT, Ferrari KD, Hösli L, Looser ZJ, Stobart JL, Duran J, Guinovart JJ, Barros LF, Weber B. Arousal-induced cortical activity triggers lactate release from astrocytes. Nature Metabolism. 2020. doi: 10.1038/s42255-020-0170-4
Romanos J, Benke D, Saab AS, Zeilhofer HU, Santello M. Differences in glutamate uptake between cortical regions impact neuronal NMDA receptor activation. Communications Biology. 2019. doi: 10.1038/s42003-019-0367-9
Baeza-Lehnert F, Saab AS, Gutiérrez R, Larenas V, Díaz E, Horn M, Vargas M, Hösli L, Stobart J, Hirrlinger J, Weber B, Barros LF. Non-Canonical Control of Neuronal Energy Status by the Na+ Pump. Cell Metabolism. 2019. doi: 10.1016/j.cmet.2018.11.005
Looser ZJ, Barrett MJP, Hirrlinger J, Weber B, Saab AS. Intravitreal AAV-Delivery of Genetically Encoded Sensors Enabling Simultaneous Two-Photon Imaging and Electrophysiology of Optic Nerve Axons. Frontiers in Cellular Neuroscience. 2018. doi: 10.3389/fncel.2018.00377
Saab AS, Nave KA. Myelin dynamics: protecting and shaping neuronal functions. Current Opinion in Neurobiology. 2017. doi: 10.1016/j.conb.2017.09.013
Stobart JL, Ferrari KD, Barrett MJP, Stobart MJ, Looser ZJ, Saab AS, Weber B. Long-term in vivo calcium imaging of astrocytes reveals distinct cellular compartment responses to sensory stimulation. Cerebral Cortex. 2018. doi: 10.1093/cercor/bhw366
Trevisiol A, Saab AS, Winkler U, Marx G, Imamura H, Möbius W, Kusch K, Nave KA, Hirrlinger J. Monitoring ATP dynamics in electrically active white matter tracts. eLife. 2017. doi: 10.7554/eLife.24241
Saab AS, Tzvetavona ID, Trevisiol A, Baltan S, Dibaj P, Kusch K, Möbius W, Goetze B, Jahn HM, Huang W, Steffens H, Schomburg ED, Pérez-Samartín A, Pérez-Cerdá F, Bakhtiari D, Matute C, Löwel S, Griesinger C, Hirrlinger J, Kirchhoff F, Nave KA. Oligodendroglial NMDA receptors regulate glucose import and axonal energy metabolism. Neuron. 2016. doi: 10.1016/j.neuron.2016.05.016
Saab AS, Nave KA. Neuroscience: A mechanism for myelin injury. Nature. 2016. doi: 10.1038/nature16865
Mayrhofer JM, Haiss F, Haenni D, Weber S, Zuend M, Barrett MJ, Ferrari KD, Maechler P, Saab AS, Stobart JL, Wyss MT, Johannssen H, Osswald H, Palmer LM, Revol V, Schuh CD, Urban C, Hall A, Larkum ME, Rutz-Innerhofer E, Zeilhofer HU, Ziegler U, Weber B. Design and performance of an ultra-flexible two-photon microscope for in vivo research. Biomedical Optics Express. 2015. doi: 10.1364/BOE.6.004228
Saab AS, Tzvetanova ID, Nave KA. The role of myelin and oligodendrocytes in axonal energy metabolism. Current Opinion in Neurobiology. 2013. doi: 10.1016/j.conb.2013.09.008
Frühbeis C, Fröhlich D, Kuo WP, Amphornrat J, Thilemann S, Saab AS, Kirchhoff F, Möbius W, Goebbels S, Nave KA, Schneider A, Simons M, Klugmann M, Trotter J, Krämer-Albers EM. Neurotransmitter-triggered transfer of exosomes mediates oligodendrocyte–neuron communication. PLoS Biology. 2013. doi: 10.1371/journal.pbio.1001604
Bai X, Saab AS, Huang W, Hoberg IK, Kirchhoff F, Scheller A. Genetic background affects human glial fibrillary acidic protein promoter activity. PLOS ONE. 2013. doi: 10.1371/journal.pone.0066873
Saab AS, Neumeyer A, Jahn HM, Cupido A, Šimek AA, Boele HJ, Scheller A, Le Meur K, Götz M, Monyer H, Sprengel R, Rubio ME, Deitmer JW, De Zeeuw CI, Kirchhoff F. Bergmann glial AMPA receptors are required for fine motor coordination. Science. 2012. doi: 10.1126/science.1221140
Fünfschilling U, Supplie LM, Mahad D, Boretius S, Saab AS, Edgar J, Brinkmann BG, Kassmann CM, Tzvetanova ID, Möbius W, Diaz F, Meijer D, Suter U, Hamprecht B, Sereda MW, Moraes CT, Frahm J, Goebbels S, Nave KA. Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity. Nature. 2012. doi: 10.1038/nature11007
Kolodziejczyk K, Saab AS, Nave KA, Attwell D. Why do oligodendrocyte lineage cells express glutamate receptors? F1000 Biology Reports. 2010. doi: 10.3410/B2-57
Möbius W, Cooper B, Kaufmann WA, Imig C, Ruhwedel T, Snaidero N, Saab AS, Varoqueaux F. Electron microscopy of the mouse central nervous system. Methods in Cell Biology. 2010. doi: 10.1016/S0091-679X(10)96020-2
Nawaz S, Kippert A, Saab AS, Werner HB, Lang T, Nave KA, Simons M. Phosphatidylinositol 4,5-bisphosphate-dependent interaction of myelin basic protein with the plasma membrane in oligodendroglial cells and its rapid perturbation by elevated calcium. Journal of Neuroscience. 2009. doi: 10.1523/JNEUROSCI.3955-08.2009