Generation of sleep spindles
The waxing of spindle waves is due to the recruitment of additional cells into the network oscillation.
Generation of sleep spindles |
|
|
|
|
|
Spindles are generated due to the capability of
thalamic reticular neurons to generate
a rebound low-threshold calcium spike and a burst of action potentials
in thalamocortical neurons, which then returns to the same thalamic
reticular cell as a barrage of excitatory postsynaptic potentials (EPSPs).
The waxing of spindle waves is due to the recruitment of additional cells into the network oscillation. |
|
Adapted from Fig. 5 from McCormick and Bal (1997)
©1998 BITS OF SLEEP (Demo) : The brain in sleep: Thalamocortical system.
