Neuropharmacology

 

 

 

"Werynska et al. Karolina has characterized synaptic transmission in the spinal dorsal horn of a phosphor-deficient glycine receptor point-mutated mouse. She found that not only was this receptor resistant to PKA-dependent phosphorylation but these mice also exhibited increased synaptic glycine and GABA release, suggesting the presence of glycine receptors not only on postsynaptic sites but also on presynaptic terminals of inhibitory dorsal horn neurons.”