Urry E, Jetter A, and Landolt HP. Assessment of CYP1A2 enzyme activity in relation to type-2 diabetes and habitual caffeine intake. Nutr Metab, in press. DOWNLOAD (PDF, 514 KB)
Urry E, Jetter A, Holst SC, Berger W, Spinas GA, Langhans W, and Landolt HP. A case-control field study on the relationships among type 2 diabetes, sleepiness, and habitual caffeine intake. J Psychopharm, in press. DOWNLOAD (PDF, 493 KB)
Landolt HP, and Dijk DJ. Genetics and Genomic Basis of Sleep in Healthy Humans. In: Principles and Practice of Sleep Medicine. Kryger MH, Roth T, Dement WC (Eds.). 6th edition. Elsevier, in press.  
Landolt HP. Importance des différences interindividuelles de sensibilité à la caféine en médecine du sommeil : rôles de  l’adénosine et de la dopamine. Médicine du Sommeil, in press. DOWNLOAD (PDF, 125 KB)
Landolt HP, and Holst SC. Ionic Control of Sleep and Wakefulness. Science 352, 517-518, 2016. [Perspective] DOWNLOAD (PDF, 333 KB)
Landolt HP. Individuelle Koffeinempfindlichkeit: Implikationen für eine personalisierte Schlafmedizin? Praxis 105, 563-568, 2016. DOWNLOAD (PDF, 237 KB)
Clark I and Landolt HP. Coffee, caffeine, and sleep: A systematic review of epidemiological studies and randomized controlled trials. Sleep Med Rev. 2016, 2016 Jan 30. pii: S1087-0792(16)00015-0.
Holst SC, Valomon A and Landolt HP. Sleep Pharmacogenetics: Personalized Sleep-Wake Therapy. Annu Rev Pharmacol Toxicol. 2016, Jan 6;56:577-603.
Landolt HP. CIRCADIAN RHYTHMS. Caffeine, the circadian clock, and sleep. Science. 2015, Sep 18;349(6254):1289.
Dauvilliers Y, Tafti M and Landolt HP. Catechol-O-methyltransferase, dopamine and sleep-wake regulation. Sleep Med Rev. 2015, Aug;22:47-53.
Urry E and Landolt HP. Adenosine, caffeine and performance: from cognitive neuroscience of sleep to sleep pharmacogenetics. Curr Top Behav Neurosci. 2015;25:331-66.
Tinguely G, Landolt HP and Cajochen C. [Sleep habits, sleep quality and sleep medicine use of the Swiss population result]. Ther Umsch. 2014, Nov;71(11):637-46.
Thomann J, Baumann CR, Landolt HP and Werth E. Psychomotor vigilance task demonstrates impaired vigilance in disorders with excessive daytime sleepiness. J Clin Sleep Med. 2014, Sep 15;10(9):1019-24.
Chellappa SL, Viola AU, Schmidt C, Bachmann V, Gabel V, Maire M, Reichert CF, Valomon A, Landolt HP and Cajochen C. Light modulation of human sleep depends on a polymorphism in the clock gene Period3. Behav Brain Res. 2014, Sep 1;271:23-9.
Valomon A, Holst SC, Bachmann V, Viola AU, Schmidt C, Zürcher J, Berger W, Cajochen C and Landolt HP. Genetic polymorphisms of DAT1 and COMT differentially associate with actigraphy-derived sleep-wake cycles in young adults. Chronobiol Int. 2014, Jun;31(5):705-14.
Olbrich E, Landolt HP and Achermann P. Effect of prolonged wakefulness on electroencephalographic oscillatory activity during sleep. J Sleep Res. 2014, Jun;23(3):253-60.
Reichert CF, Maire M, Gabel V, Viola AU, Kolodyazhniy V, Strobel W, Götz T, Bachmann V, Landolt HP Cajochen C and Schmidt C. Insights into behavioral vulnerability to differential sleep pressure and circadian phase from a functional ADA polymorphism. J Biol Rhythms. 2014, Apr;29(2):119-30.
Holst SC, Bersagliere A, Bachmann V, Berger W, Achermann P, and Landolt HP. Dopaminergic role in regulating neurophysiological markers of sleep homeostasis in humans. J Neurosci. 2014, Jan 8;34(2):566-73.
Maire M, Reichert CF, Gabel V, Viola AU, Krebs J, Strobel W, Landolt HP. Bachmann V, Cajochen C and Schmidt C. Time-on-task decrement in vigilance is modulated by inter-individual vulnerability to homeostatic sleep pressure manipulation. Front Behav Neurosci.. 2014 Mar 6;8:59.
Reichert CF, Maire M, Gabel V, Hofstetter M, Viola AU, Kolodyazhniy V, Strobel W, Goetz T, Bachmann V, Landolt HP Cajochen C and Schmidt C. The circadian regulation of sleep: impact of a functional ADA-polymorphism and its association to working memory improvements. PLoS One. 2014, 9(12):e113734.  
Bosch OG, Rihm JS, Scheidegger M, Landolt HP, Stämpfli P, Brakowski J, Esposito F, Rasch B, and Seifritz E. Sleep deprivation increases dorsal nexus connectivity to the dorsolateral prefrontal cortex in humans. Proc Natl Acad Sci USA, 110, 19597-15602 (2013
Hefti K, Holst SC, Sovago J, Bachmann V, Buck A, Ametamey SM, Scheidegger M, Bethold T, Gomez-Mancilla B, Seifritz E and Landolt HP. Increased metabotropic glutamate receptor subtype 5 availability in human brain after one night without sleep. Biol Psychiatry, 73, 161-168 (2013)
Landolt HP, Rétey JV and Adam M. Reduced neurobehavioral impairment from sleep deprivation in older adults: Contribution of adenosinergic mechanisms. Front Neurol, 3, 62 (2012)
Chellappa SL, Viola AU, Schmidt C, Bachmann V, Gabel V, Maire M, Reichert CF, Valomon A, Götz T, Landolt HP and Cajochen C. Human melatonin and alerting response to blue-enriched light depend on a polymorphism in the clock gene PER3. J Clin Endocrinol Metab, 97, E433-E437 (2012)
Bachmann V, Klein C, Bodenmann S, Schäfer N, Berger W, Brugger P and Landolt HP. The BDNF Val66Met polymorphism modulates sleep intensity: EEG frequency- and state-specificity. Sleep, 35, 335-344, (2012)
Bodenmann S, Hohoff C, Freitag C, Deckert J, Rétey JV, Bachmann V and Landolt HP. Polymorphisms of ADORA2A modulate psychomotor vigilance and the effects of caffeine on neurobehavioral performance and sleep EEG after sleep deprivation. Br J Pharmacol, 165, (2012)



Landolt HP. Genetic effects. In: Encyclopedia of Sleep. Kushida C . (Ed.). Vol. 1, Academic Press, pp. 251-256, 2013.
Holst SC, and Landolt HP. Die Rolle metabotroper Glutamat-Rezeptoren vom Subtyp 5 bei den Folgen von Schlafentzug. Swiss Med Forum 13, 970-971, 2013.
Landolt HP, and Urry E. Functional neuroimaging: Sedating medication effects. In: Neuroimaging of sleep and sleep disorders. Nofzinger E, Maquet P and Thorpy M (Eds.) Cambridge University Press, Cambridge, UK, pp. 395-405, 2013
Landolt HP (2012) “No Thanks, Coffee Keeps Me Awake”: Individual Caffeine Sensitivity Depends on ADORA2A Genotype. Sleep 35, 899-900.
Landolt HP, (2012). Génétique du Sommeil Normal et des Rythmes Circadiens. In: Les Troubles du Sommeil. Billiard M, Dauvilliers Y (Eds). 2nd edition. pp. 45-57
Landolt HP, (2011). Sleep homeostasis, adenosine, caffeine, and narcolepsy. In: Narcolepsy and Hypersomnia. Bassetti CL, Scammell TE, Baumann CR (Eds). Humana Press, Springer, New York pp. 85-92
Landolt HP, (2011). Genetic effects. In: Encyclopedia of Sleep. Kushida CA (Ed). In press.
Landolt HP, (2011) Genetic determination of sleep EEG profiles in healthy humans. Prog Brain Res 193, 51-61
Landolt HP, Dijk DJ (2011). Genetic Basis of Sleep in Healthy Humans. In: Principles and Practice of Sleep Medicine. Kryger MH (Ed.). 5th edition. pp. 175-183.
Landolt HP, Wehrle R (2009). Antagonism of serotonergic 5-HT2A/2C receptors: mutual improvement of sleep, cognition and mood? Eur J Neurosci 29, 1795-1809.
Landolt HP, Genotype-dependent differences in sleep, vigilance and response to stimulants. Curr Pharm Des, 14:3396-3407 (2008)
Landolt HP, Sleep homeostasis: a role for adenosine in humans? Biochem Pharmacol, 75, 2070-2079 (2008)